If using the original ScanWizard EZ on Windows 10, try running the installer in Compatibility Mode for Windows 7 or XP. WIA Drivers:
: This is a highly recommended third-party scanning application from Hamrick Software . It includes built-in drivers for over 7,000 scanners, including many legacy Microtek models, allowing them to work on the latest versions of Windows, macOS, and Linux without needing original drivers. Microtek Scanmaker S460 Driver Download