The "Ami" part pays homage to the Amiga’s custom chipset—Paula for audio, Denise for graphics, and Agnus for memory control. The "win64" part acknowledges the host architecture: the 64-bit computing environment that powers most of the world’s desktops today.
As of today, the Amiwin64 scene is small but vibrant. Projects like (for Linux/Windows) and WinUAE (the gold standard on Windows) are updated weekly, fixing obscure bugs from 1992. There are even distributions that package the entire experience into a single, portable executable—a "ROM-in-a-file" that launches the Amiga Workbench in a window faster than Explorer loads a folder. Amiwin64