A: No. The control is 32-bit only, which is why it must be registered in SysWOW64 on 64-bit Windows. It will run under WOW64 emulation.
: Some users have reported that installing the Chinese (Simplified) language pack for Office can force the control to appear if it was previously missing.
If "Microsoft Barcode Control 16.0" does not appear in your "More Controls" list, it is likely because:
: Sites like TEC-IT and BarCodeWiz offer robust ActiveX controls that support 1D and 2D barcodes (like QR codes) for all Office versions.
However, if you legally own an old perpetual license of Office 2010, 2013, or 2016, the file MSBCODE9.OCX may already exist on your system.
A: No. Support ended in 2018. Any issues are "use at your own risk."