Officially, Corel Corporation (now Alludo) did not release a "Portable" version of CorelDRAW X5. The software was designed as a standard Windows application requiring a full installation process, registry entries, and specific system drivers.
Ensure your Windows 10 has legacy .NET Framework 3.5 enabled, as X5 relies on these older libraries to render the workspace. Pros and Cons of the Portable Version Coreldraw X5 Portable Windows 10
You can use "application virtualization" tools to make a legitimate portable version. This is 100% legal if you own a license. Officially, Corel Corporation (now Alludo) did not release