Sampling Size Calculation [BEST]

If you run 20 different statistical tests on the same dataset, you will find a "statistically significant" result purely by chance (due to a Type I error). If you plan to test multiple hypotheses, you must adjust your significance level (e.g., using Bonferroni correction: α = 0.05 / 20 = 0.0025). This, in turn, .

Regulatory bodies like the FDA and EMA require a prospective sample size calculation in every clinical trial protocol. The justification must be transparent, reproducible, and clinically sound. sampling size calculation

Are you comparing two groups (t-test), looking for a relationship (correlation), or just estimating a mean? If you run 20 different statistical tests on

To calculate your sample size, you generally need to plug four specific variables into a formula: A. Confidence Level (Alpha) looking for a relationship (correlation)