Yes, almost always. Reinstalling Windows changes the operating system’s unique identifiers, which are part of the Hardware ID calculation. You will need to reactivate PE Design 11 after a clean Windows install.
If the software is still installed and activated, go to Help > About PE Design 11. The serial number is often listed there. If not, check your original purchase email or contact Brother with your receipt. pe design 11 hardware id
Write down the Hardware ID exactly as shown. Capitalization and dashes matter. Take a photo with your phone or use a screenshot tool. One typo will break the activation. Yes, almost always