Generally, yes. It is safe to run if downloaded from an official Autodesk source or an authorized distributor.
If an employee runs xf-adsk2013 x64.exe on a company machine, the business faces:
The "xf" in the filename stands for X-Force, a well-known group in the software cracking community. The "adsk2013" identifies its target as the Autodesk 2013 product line, and "x64" indicates it is built for 64-bit Windows operating systems.

